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Zhang J, Lin Y, Lin Z, Wei Q, Qian J, Ruan R et al

Clinical evidence demonstrated that increased ROS production and decreased NO bioavailability were in hypertensive patients [114]

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High concentrations of GSH also inhibit melanin production, either through direct binding with polyphenol oxidases required for melanin production, or by reduction of radical melanin precursors (e.g., dopaquinone) with the latter leading to formation of thiol-quinone conjugates used in pheomelanogenesis 2527